Avacopan (Standard), CAS 1346623-17-3

Avacopan (Standard), CAS 1346623-17-3
Artikelnummer
MEXHY-17627R-0
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MedChemExpress

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Product Description: Avacopan (Standard) is the analytical standard of Avacopan. This product is intended for research and analytical applications. Avacopan (CCX168) is a potent, selective and orally available complement 5a receptor (C5aR) inhibitor with an IC50 of 0.1 nM.

Formula: N/A

References: [1]Bekker P, et al. Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study. PLoS One. 2016 Oct 21;11(10):e0164646./[2]Xiao H, et al. C5a receptor (CD88) blockade protects against MPO-ANCA GN. J Am Soc Nephrol. 2014 Feb;25(2):225-31.

CAS Number: 1346623-17-3

Molecular Weight: N/A

Research Area: Inflammation/Immunology

Target: Complement System
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Artikelnummer MEXHY-17627R-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-17627R-0
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Verpackungseinheit Get quote
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