AZD3147, CAS 1101810-02-9

Product Description: AZD3147 is a potent, orally active, selective dual inhibitor of mTORC1 and mTORC2 with an IC50 value of 1.5 nM. AZD3147 also has a selective effect on PI3K[1].

Applications: Cancer-Kinase/protease

Formula: C24H31N5O4S2

References: [1]Kurt G Pike, et al. Discovery of AZD3147: a potent, selective dual inhibitor of mTORC1 and mTORC2. J Med Chem. 2015 Mar 12;58(5):2326-49./[2]Michaela Kunova Bosakova, et al. Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies. Hum Mol Genet. 2018 Mar 15;27(6):1093-1105./[3]Rebecca Waetzig, et al. Comparing mTOR inhibitor Rapamycin with Torin-2 within the RIST molecular-targeted regimen in neuroblastoma cells. Int J Med Sci. 2021 Jan 1;18(1):137-149.

CAS Number: 1101810-02-9

Molecular Weight: 517.66

Compound Purity: 99.93

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: mTOR

• Artikelnummer: MEXHY-12652-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-12652-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK