BCL-xL/BCL-2 ligand 1, CAS 2941091-91-2

BCL-xL/BCL-2 ligand 1, CAS 2941091-91-2
Artikelnummer
MEXHY-161415-0
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MedChemExpress

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Product Description: BCL-xL/BCL-2 ligand 1 (compound 72-1) is a BCL-xL and BCL-2 protein ligand. BCL-xL/BCL-2 ligand 1 can be connected to the E3 ligase by a linker to form PROTACs (HY-161410)[1][2].

Formula: C48H53ClF3N5O7S3

References: [1]Guangrong Zheng, et al. Bcl-xl/bcl-2 dual degraders for treatment of cancers. WO2023107606A1./[2]Nayak D, et al. Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun. 2024 Mar 29;15(1):2743.

CAS Number: 2941091-91-2

Molecular Weight: 1000.61

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Ligands for E3 Ligase
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Artikelnummer MEXHY-161415-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-161415-0
Green Labware Nein
Verpackungseinheit Get quote
Mengeneinheit STK
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