Bedaquiline (Standard), CAS 843663-66-1

Product Description: Bedaquiline (Standard) is the analytical standard of Bedaquiline. This product is intended for research and analytical applications. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit[1]. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis[2].

Formula: N/A

References: [1]Jang JC, et al. Bedaquiline susceptibility test for totally drug-resistant tuberculosis Mycobacterium tuberculosis. J Microbiol. 2017 Apr 20./[2]Pang Y, et al. In Vitro Activity of Bedaquiline against Nontuberculous Mycobacteria in China. Antimicrob Agents Chemother. 2017 Apr 24;61(5)./[3]Chahine EB, et al. Bedaquiline: a novel diarylquinoline for multidrug-resistant tuberculosis. Ann Pharmacother. 2014 Jan;48(1):107-15./[4]Sarathy JP, et al. TBAJ-876 displays Bedaquiline-like mycobactericidal potency without retaining the parental drug's uncoupler activity. Antimicrob Agents Chemother. 2019 Nov 11.

CAS Number: 843663-66-1

Molecular Weight: N/A

Research Area: Infection

Target: Antibiotic;Bacterial

• Artikelnummer: MEXHY-14881R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-14881R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK