Bendamustine (hydrochloride) (Standard), CAS 3543-75-7

Product Description: Bendamustine (hydrochloride) (Standard) is the analytical standard of Bendamustine (hydrochloride). This product is intended for research and analytical applications. Bendamustine hydrochloride (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine hydrochloride activats DNA-damage stress response and apoptosis. Bendamustine hydrochloride has potent alkylating, anticancer and antimetabolite properties[1].

Formula: N/A

References: [1]Leoni LM, et al. Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents. Clin Cancer Res. 2008 Jan 1;14(1):309-17./[2]Cives M, et al. Bendamustine overcomes resistance to melphalan in myeloma cell lines by inducing cell death through mitotic catastrophe. Cell Signal. 2013 May;25(5):1108-17./[3]Ackler S, et al. Navitoclax (ABT-263) and bendamustine ± rituximab induce enhanced killing of non-Hodgkin's lymphoma tumours in vivo. Br J Pharmacol. 2012 Oct;167(4):881-91.

CAS Number: 3543-75-7

Molecular Weight: N/A

Research Area: Cancer

Target: Apoptosis;DNA Alkylator/Crosslinker

• Artikelnummer: MEXHY-B0077R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0077R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK