Product Description: Benzyl-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Benzyl-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Applications: Cancer-programmed cell death
Formula: C11H15N3O2
References: [1]Steinebach C, et al. A MedChem toolbox for cereblon-directed PROTACs. Medchemcomm. 2019 May 28;10(6):1037-1041.