Berotralstat (Standard), CAS 1809010-50-1

Product Description: Berotralstat (Standard) is the analytical standard of Berotralstat. This product is intended for research and analytical applications. Berotralstat (BCX7353) is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE[1][2].

Formula: N/A

References: [1]Zuraw B, et al. Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial [published online ahead of print, 2020 Oct 21]. J Allergy Clin Immunol. 2020;S0091-6749(20)31484-6./[2]Manning ME, et al. Berotralstat (BCX7353) is a novel oral prophylactic treatment for hereditary angioedema: Review of phase II and III studies. Allergy Asthma Proc. 2021;42(4):274-282.

CAS Number: 1809010-50-1

Molecular Weight: N/A

Research Area: Others

Target: Ser/Thr Protease

• Artikelnummer: MEXHY-109127R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-109127R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK