Bezafibrate (Standard), CAS 41859-67-0

Product Description: Bezafibrate (Standard) is the analytical standard of Bezafibrate. This product is intended for research and analytical applications. Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent.

Formula: N/A

References: [1]Willson TM, et al. The PPARs: from orphan receptors to drug discovery. J Med Chem. 2000 Feb 24;43(4):527-50./[2]Usui-Ouchi A, et al. The peroxisome proliferator-activated receptor pan-agonist bezafibrate suppresses microvascular inflammatory responses of retinal endothelial cells and vascular endothelial growth factor production in retinal pigmented epithelial cells. Int Immunopharmacol. 2017 Nov;52:70-76./[3]Franko A, et al. Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice. Mol Metab. 2017 Jan 6;6(3):256-266.

CAS Number: 41859-67-0

Molecular Weight: N/A

Research Area: Metabolic Disease; Cardiovascular Disease

Target: PPAR

• Artikelnummer: MEXHY-B0637R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0637R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK