BF389, CAS 127245-22-1

BF389, CAS 127245-22-1
Artikelnummer
MEXHY-106897-0
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MedChemExpress

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Product Description: BF389 (Biofor 389) is an orally active anti-inflammatory and analesis agent. BF389 is also an inhibitor of cyclooxygenase and 5-lipoxygenase, with IC50s of 4 and 8 ug/mL for COX-1 and COX-2 respectively. BF389 can be used for arthritis research[1][2][3].

Applications: COVID-19-immunoregulation

Formula: C20H29NO3

References: [1]Bendele AM, et al. Anti-inflammatory activity of BF389, a Di-T-butylphenol, in animal models of arthritis. J Pharmacol Exp Ther. 1992 Jan;260(1):300-5./[2]Wong S, et al. Antiarthritic profile of BF-389--a novel anti-inflammatory agent with low ulcerogenic liability. Agents Actions. 1992 Sep;37(1-2):90-8./[3]Mitchell JA, et al. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11693-7.

CAS Number: 127245-22-1

Molecular Weight: 331.45

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: COX;Lipoxygenase
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Artikelnummer MEXHY-106897-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-106897-0
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Verpackungseinheit Get quote
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