Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn), CAS 3030990-42-9

Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Cys modified with M6Pn), CAS 3030990-42-9
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MEXHY-158033-0
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MedChemExpress

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Product Description: Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 (Compound 24, Cys modified with M6Pn) is a mannose-6-phosphate (M6Pn)-peptide conjugate capable of binding to targeted ligands of various proteins and successfully internalizing and degrading them through M6PR. Biotin-εNle-CKCKC-γAbu-CKCKCG-NH2 can be utilized in the research of lysosomal targeting chimeras (LYTACs) based on M6Pn[1].

Applications: Cancer-programmed cell death

Formula: C124H230N20O63P6S7

References: [1]Stevens CM, et al. Development of Oligomeric Mannose-6-phosphonate Conjugates for Targeted Protein Degradation. ACS Med Chem Lett. 2023;14(6):719-726. Published 2023 Mar 3.

CAS Number: 3030990-42-9

Molecular Weight: 3419.55

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: LYTACs
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Artikelnummer MEXHY-158033-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-158033-0
Green Labware Nein
Verpackungseinheit Get quote
Mengeneinheit STK
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