Product Description: Biotin-YVAD-FMK is an inhibitor for vacuolar processing enzyme (VPE), with a 64% inhibition at 5 μM. Biotin-YVAD-FMK is an irreversible substrate for caspase 1[1][2].
Formula: C32H45FN6O9S
References: [1]Hatsugai N, et al., A plant vacuolar protease, VPE, mediates virus-induced hypersensitive cell death. Science. 2004 Aug 6;305(5685):855-8. /[2]Case CL, et al., Asc modulates the function of NLRC4 in response to infection of macrophages by Legionella pneumophila. mBio. 2011 Sep 1;2(4):e00117-11.
Molecular Weight: 708.80
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Others