Bizelesin, CAS 129655-21-6

Product Description: Bizelesin (NSC 615291; U-77779) is an AT-specific DNA alkylating agent that can generate DNA interstrand crosslinks, effectively inhibit DNA replication, and has potential anticancer activity[1].

Applications: Cancer-programmed cell death

Formula: C43H36Cl2N8O5

References: [1]J M Woynarowski, et al. AT-rich islands in genomic DNA as a novel target for AT-specific DNA-reactive antitumor drugs. J Biol Chem. 2001 Nov 2;276(44):40555-66. /[2]J M Woynarowski, et al. Effects of bizelesin (U-77,779), a bifunctional alkylating minor groove binder, on replication of genomic and simian virus 40 DNA in BSC-1 cells. Biochim Biophys Acta. 1997 Jul 17;1353(1):50-60. 

CAS Number: 129655-21-6

Molecular Weight: 815.70

Compound Purity: 95.07

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: DNA Alkylator/Crosslinker

• Artikelnummer: MEXHY-111397-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-111397-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK