C108297, CAS 864972-30-5

Product Description: C108297 is a selective glucocorticoid receptor (GR) modulator (GR binding Ki 0.7 nM; GR reporter gene functional Ki 0.6 nM). C108297 attenuates obesity by reducing caloric intake and increasing lipolysis and fat oxidation, and in addition attenuates inflammation[1][2].

Applications: Metabolism-sugar/lipid metabolism

Formula: C30H36FN3O4S

References: [1]Clark RD, et al. 1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity. Bioorg Med Chem Lett. 2008;18(4):1312-1317./[2]van den Heuvel JK, et al. Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation. Br J Pharmacol. 2016;173(11):1793-1804.

CAS Number: 864972-30-5

Molecular Weight: 553.69

Compound Purity: 99.97

Research Area: Metabolic Disease; Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Glucocorticoid Receptor

• Artikelnummer: MEXHY-125096-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-125096-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK