CDK9-IN-7, CAS 2369981-71-3

CDK9-IN-7, CAS 2369981-71-3
Artikelnummer
MEXHY-126251-100
Verpackungseinheit
100 mg
Hersteller
MedChemExpress

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Product Description: CDK9-IN-7 (compound 21e) is a selective, highly potent, and orally active CDK9/cyclin T inhibitor (IC50=11 nM), which exhibits more potent over other CDKs (CDK4/cyclinD=148 nM; CDK6/cyclinD=145 nM). CDK9-IN-7 shows antitumor activity without obvious toxicity. CDK9-IN-7 induces NSCLC cell apoptosis, arrests the cell cycle in the G2 phase, and suppresses the stemness properties of NSCLC[1].

Applications: Cancer-Kinase/protease

Formula: C29H37N7O2S

References: [1]Wang X, et al. Novel cyclin-dependent kinase 9 (CDK9) inhibitor with suppression of cancer stemness activity against non-small-cell lung cancer. Eur J Med Chem. 2019 Jul 25;181:111535.

CAS Number: 2369981-71-3

Molecular Weight: 547.71

Compound Purity: 98.05

Research Area: Cancer

Solubility: DMSO : 62.5 mg/mL (ultrasonic)

Target: Apoptosis;CDK
Mehr Informationen
Artikelnummer MEXHY-126251-100
Hersteller MedChemExpress
Hersteller Artikelnummer HY-126251-100
Green Labware Nein
Verpackungseinheit 100 mg
Mengeneinheit STK
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