Product Description: Cefatrizine (BL-S-640) is an orally active and broad-spectrum cephalosporin antibiotic. Cefatrizine is also a eEF2K inhibitor, with anti-proliferative activity in human breast cancer cells, which could induce ER stress, leading to cell death. Cefatrizine can be used in studies of cancer and bacterial infection[1][2].
Applications: COVID-19-immunoregulation
Formula: C18H18N6O5S2
References: [1]Yao Z, et al. Integrative bioinformatics and proteomics-based discovery of an eEF2K inhibitor (cefatrizine) with ER stress modulation in breast cancer cells. Mol Biosyst. 2016 Mar;12(3):729-36. /[2]Leitner F, et al. BL-S640, a cephalosporin with a broad spectrum of antibacterial activity: bioavailability and therapeutic properties in rodents. Antimicrob Agents Chemother. 1975 Mar;7(3):306-10.
CAS Number: 51627-14-6
Molecular Weight: 462.50
Research Area: Cancer; Infection
Solubility: H2O : 250 mg/mL (ultrasonic)
Target: Antibiotic;Apoptosis;Bacterial