CGS 35601, CAS 849066-09-7

Product Description: CGS 35601 is the inhibitor for endothelin-converting enzyme-1 (ECE-1), neutral endopeptidase 24.11 (NEP), and angiotensin-converting enzyme (ACE), with IC50s of 55, 2, and 22 nM, respectively. CGS 35601 suppresses the big endothelin-1 (big ET-1)- and angiotensin I-induced pressor response, and enhances circulation of atrial natriuretic peptide (ANP), regulates the cardiovascular function in SD rats[1].

Formula: C23H31N3O4S

References: [1]Trapani AJ, et al., CGS 35601 and its orally active prodrug CGS 37808 as triple inhibitors of endothelin-converting enzyme-1, neutral endopeptidase 24.11, and angiotensin-converting enzyme. J Cardiovasc Pharmacol. 2004 Nov;44 Suppl 1:S211-5.

CAS Number: 849066-09-7

Molecular Weight: 445.58

Research Area: Cardiovascular Disease

Target: Angiotensin-converting Enzyme (ACE)

• Artikelnummer: MEXHY-18211-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-18211-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK