Chembridge-5861528, CAS 332117-28-9

Product Description: Chembridge-5861528 (TCS 5861528) is a potent TRPA1 channel antagonist that antagonizes similarly allyl isothiocyanate- and 4-HNE-evoked TRPA1 responses, with IC50 values of 14.3 μM and 18.7 μM, respectively. Chembridge-5861528 shows antihypersensitivity activities[1].

Applications: Neuroscience-Neuromodulation

Formula: C19H23N5O3

References: [1]Wei H, et al. Attenuation of mechanical hypersensitivity by an antagonist of the TRPA1 ion channel in diabetic animals. Anesthesiology. 2009 Jul;111(1):147-54./[2]Wei H, et al. Spinal TRPA1 ion channels contribute to cutaneous neurogenic inflammation in the rat. Neurosci Lett. 2010 Aug 2;479(3):253-6.

CAS Number: 332117-28-9

Molecular Weight: 369.42

Compound Purity: 99.76

Research Area: Metabolic Disease; Inflammation/Immunology; Neurological Disease

Solubility: DMSO : 120 mg/mL (ultrasonic)

Target: TRP Channel

• Artikelnummer: MEXHY-15065-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15065-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK