Chlorotrianisene (Standard), CAS 569-57-3

Product Description: Chlorotrianisene (Standard) is the analytical standard of Chlorotrianisene. This product is intended for research and analytical applications. Chlorotrianisene is a long-acting non-steroidal estrogen and an orally active estrogen receptor modulator. Chlorotrianisene exhibits antiestrogenic activity. Chlorotrianisene potently inhibits the enzyme COX-1 and inhibits platelet aggregation in whole blood[1][2][3].

Formula: N/A

References: [1]Ruenitz PC, et al. Estrogenic tamoxifen derivatives: categorization of intrinsic estrogenicity in MCF-7 cells. J Steroid Biochem Mol Biol. 1997 Nov-Dec;63(4-6):203-9./[2]Lounkine E, et al. Large-scale prediction and testing of drug activity on side-effect targets. Nature. 2012 Jun 10;486(7403):361-7./[3]Kupfer D, et al. Inactivation of the uterine estrogen receptor binding of estradiol during P-450 catalyzed metabolism of chlorotrianisene (TACE). Speculation that TACE antiestrogenic activity involves covalent binding to the estrogen receptor. FEBS Lett. 1990 Feb 12;261(1):59-62.

CAS Number: 569-57-3

Molecular Weight: N/A

Research Area: Endocrinology; Cardiovascular Disease

Target: COX;Estrogen Receptor/ERR

• Artikelnummer: MEXHY-B2158R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B2158R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK