Cholesterol hemisuccinate (Tris salt), CAS 102601-49-0

Product Description: Cholesterol hemisuccinate Tris salt (CHS-Tris) is often used to replace cholesterol in protein crystallography, biochemical studies of proteins, and pharmacology. CHS-Tris and Lauryl Maltose Neopentyl Glycol (LMNG) or n-Dodecyl-β-D-Maltoside (DDM) are used together for the solubilization of membrane proteins while maintaining structural integrity and activity. Cholesteryl succinate also reportedly exhibits antiproliferative activity.

Applications: Cancer-programmed cell death

Formula: C35H61NO7

References: [1]Ray SD, et al. Protection of acetaminophen-induced hepatocellular apoptosis and necrosis by cholesteryl hemisuccinate pretreatment. J Pharmacol Exp Ther. 1996 Dec;279(3):1470-83./[2]Varshosaz J, et al. Folated synperonic-cholesteryl hemisuccinate polymeric micelles for the targeted delivery of docetaxel in melanoma. Biomed Res Int. 2015;2015:746093.

CAS Number: 102601-49-0

Molecular Weight: 607.86

Research Area: Cancer

Solubility: 10 mM in Ethanol

Target: Apoptosis;DNA/RNA Synthesis;Necroptosis;Topoisomerase

• Artikelnummer: MEXHY-W010800A-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W010800A-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK