Ciraparantag (acetate), CAS 1644388-83-9

Product Description: Ciraparantag (PER977) acetate is a thrombin and factor Xa inhibitor. Ciraparantag acetate is a broad-spectrum reversal agent for anticoagulants, including low molecular weight heparins, unfractionated heparins, and some direct oral anticoagulants, but not VKAs[1][2][3][4].

Applications: Neuroscience-Neuromodulation

Formula: C22H48N12O2.xC2H4O2

References: [1]Das A, et al. Novel antidotes for target specific oral anticoagulants. Exp Hematol Oncol. 2015 Sep 15;4:25. [Content Brief]/[2]Gomez-Outes A, et al. Specific antidotes in development for reversal of novel anticoagulants: a review. Recent Pat Cardiovasc Drug Discov. 2014;9(1):2-10. [Content Brief]/[3]Hu TY, et al. Reversing anticoagulant effects of novel oral anticoagulants: role of ciraparantag, andexanet alfa, and idarucizumab. Vasc Health Risk Manag. 2016 Feb 17;12:35-44. [Content Brief]/[4]Honickel M, et al. The Reversal of Direct Oral Anticoagulants in Animal Models. Shock. 2017 Aug;48(2):144-158. [Content Brief]

CAS Number: 1644388-83-9

Molecular Weight: N/A

Compound Purity: 98.0

Research Area: Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Factor Xa

• Artikelnummer: MEXHY-18660B-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-18660B-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK