Clofazimine (Standard), CAS 2030-63-9

Product Description: Clofazimine (Standard) is the analytical standard of Clofazimine. This product is intended for research and analytical applications. Clofazimine is an orally-active anti-mycobacterial agent with a wide range of anti-mycobacterial activity including leprosy and tuberculosis. Clofazimine exerts anti-inflammatory activities and anti-tumor activities by interfering DNA replication and inhibiting IL2 (IC50 = 1.10 ± 0.26 μM, Jurkat T) production. Clofazimine can be used in mycobacterial and cancer research[1][2][3][4][5].

Formula: N/A

References: [1]Arbiser JL, et al. Clofazimine: a review of its medical uses and mechanisms of action. J Am Acad Dermatol. 1995 Feb;32(2 Pt 1):241-7./[2]Cholo MC, et al. Clofazimine: current status and future prospects. J Antimicrob Chemother. 2012 Feb;67(2):290-8./[3]Riccardi N, et al. Clofazimine: an old drug for never-ending diseases. Future Microbiol. 2020，15:557-566./[4]Ammerman NC, et al. Clofazimine has delayed antimicrobial activity against Mycobacterium tuberculosis both in vitro and in vivo. J Antimicrob Chemother. 2017，72(2):455-461. /[5]Durusu İZ, et al. Anti-cancer effect of clofazimine as a single agent and in combination with cisplatin on U266 multiple myeloma cell line. Leuk Res. 2017，55:33-40. /[6]Ren YR, et al. Clofazimine Inhibits Human Kv1.3 Potassium Channel by Perturbing Calcium Oscillation in T Lymphocytes. PLoS One. 2008，3(12):e4009.

CAS Number: 2030-63-9

Molecular Weight: N/A

Research Area: Cancer; Infection; Inflammation/Immunology

Target: Antibiotic;Apoptosis;Bacterial;DNA/RNA Synthesis;Interleukin Related

• Artikelnummer: MEXHY-B1046R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B1046R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK