Compound 48/80, CAS 94724-12-6

Product Description: Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways[1][2].

Applications: Cancer-programmed cell death

Formula: C32H45N3O3

References: [1]Schemann M, et al. The mast cell degranulator compound 48/80 directly activates neurons. PLoS One. 2012;7(12):e52104. /[2]Wang YH, Taché Y, Harris AG, Kreutner W, Daly AF, Wei JY. Desloratadine prevents compound 48/80-induced mast cell degranulation: visualization using a vital fluorescent dye technique. Allergy. 2005;60(1):117-124. /[3]Darzynkiewicz Z, Carter S. Compound 48/80 impairs cytokinesis in murine leukemic cells. J Cell Physiol. 1984;119(1):1-6.

CAS Number: 94724-12-6

Molecular Weight: 519.72

Compound Purity: 99.98

Research Area: Cancer; Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Others

• Artikelnummer: MEXHY-115768-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-115768-10.1
• Green Labware: Nein
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK