Covidcil-19, CAS 1225177-95-6

Product Description: Covidcil-19 (compound C5) avidly binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with a Kd of 11 nM. Covidcil-19 stabilizes the hairpin’s folded state and impairs frameshifting in cells. Covidcil-19 reduces frameshifting efficiency of the SARS-CoV-2 FSE and does not affect SARS-CoV-2 FSE RNA levels. Covidcil-19 inhibits a process essential for SARS-CoV-2 viral propagation[1].

Formula: C16H14N4O2

References: [1]Hafeez S Haniff, et al.  Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders. ACS Cent Sci. 2020 Oct 28;6(10):1713-1721.

CAS Number: 1225177-95-6

Molecular Weight: 294.31

Research Area: Infection

Solubility: 10 mM in DMSO

Target: SARS-CoV

• Artikelnummer: MEXHY-W728005-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W728005-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK