Product Description: COX-2-IN-43 (Compound MYM4) is a COX-2 inhibitor (IC50: 0.983 and 0.247 μM for COX-1 and COX-2 respectively). COX-2-IN-43 inhibits cancer cell proliferation and colonization, induces apoptosis[1].
Formula: C18H11Cl2F3N2O3
References: [1]Hawash M, et al. Exploration of isoxazole analogs: Synthesis, COX inhibition, anticancer screening, 3D multicellular tumor spheroids, and molecular modeling. Eur J Med Chem. 2024 Apr 15;271:116397.
CAS Number: 1023524-40-4
Molecular Weight: 431.19
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Apoptosis;COX