Product Description: CPG-52364 (compound 2) is a TLR9 antagonist. CPG-52364 inhibits the HEK293-hTLR9 cell with an IC50 value of 4.6 nM[1].
Formula: C27H36N6O3
References: [1]Manabu Watanabe, et al. Dihydropyrrolo[2,3-d]pyrimidines: Selective Toll-Like Receptor 9 Antagonists from Scaffold Morphing Efforts. ACS Med Chem Lett. 2014, 5, 11.
CAS Number: 1093135-60-4
Molecular Weight: 492.61
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Toll-like Receptor (TLR)