CPI-203, CAS 1446144-04-2

Product Description: CPI-203 is a novel potent, selective and cell permeable inhibitor of BET bromodomain, with an IC50 value of appr 37 nM (BRD4 α-screen assay).

Applications: Cancer-Kinase/protease

Formula: C19H18ClN5OS

References: [1]Devaiah BN, et al. BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain. Proc Natl Acad Sci U S A. 2012 May 1;109(18):6927-32./[2]Moros A, et al. Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma. Leukemia. 2014 Oct;28(10):2049-59

CAS Number: 1446144-04-2

Molecular Weight: 399.90

Compound Purity: 98.07

Research Area: Cancer

Solubility: DMSO : ≥ 47 mg/mL

Target: Apoptosis;Epigenetic Reader Domain

• Artikelnummer: MEXHY-15846-50
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15846-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK