(Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2)(PF6)2

Product Description: [Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 (Compound 3) is a copper complex, which inhibits cell viability of HCT116, HCT116DoxR, A2780 and fibroblasts, with IC50s of 0.13, 0.15, 0.66 and 6.24 μM, respectively. [Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 induces apoptosis and autophagy, and arrests cell cycle at G0/G1 phase in HCT116DoxR. [Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 exhibits antimetastatic efficacy[1].

Formula: C52H38Cl2Cu2F12N6O2P2 2-

References: [1]Choroba K, et al., Copper(II) Complexes with 2,2':6',2″-Terpyridine Derivatives Displaying Dimeric Dichloro-μ-Bridged Crystal Structure: Biological Activities from 2D and 3D Tumor Spheroids to In Vivo Models. J Med Chem. 2024 Apr 11;67(7):5813-5836.

Molecular Weight: 1266.82

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Autophagy

• Artikelnummer: MEXHY-158117-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-158117-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK