d-KLA Peptide, CAS 286380-05-0

Product Description: d-KLA Peptide is a synthetic pro-apoptotic peptide. d-KLA Peptide can specifically target mitochondria and induce apoptosis by destroying the mitochondrial membrane. d-KLA Peptide activates biochemical pathways associated with apoptosis, including the activation of caspase family proteins and PARP (poly ADP ribose polymerase). d-KLA Peptide can be used to carry and deliver genes or small molecules to enhance anti-tumor effects[1][2].

Formula: C72H138N20O15

References: [1]Kim H Y, et al. The cell penetrating ability of the proapoptotic peptide, KLAKLAKKLAKLAK fused to the N-terminal protein transduction domain of translationally controlled tumor protein, MIIYRDLISH[J]. Biomaterials, 2011, 32(22): 5262-5268./[2]Ko Y T, et al. Cationic liposomes loaded with proapoptotic peptide D-(KLAKLAK) 2 and Bcl-2 antisense oligodeoxynucleotide G3139 for enhanced anticancer therapy[J]. Molecular Pharmaceutics, 2009, 6(3): 971-977.

CAS Number: 286380-05-0

Molecular Weight: 1523.99

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Caspase;Mitochondrial Metabolism;PARP

• Artikelnummer: MEXHY-P10285-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P10285-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK