DCLK1-IN-5, CAS 3028774-14-0

Product Description: DCLK1-IN-5 (Compound a24) is a DCLK1 inhibitor (IC50: 179.7 nM). DCLK1-IN-5 inhibits lipopolysaccharide (HY-D1056)-induced inflammation via inhibiting DCLK1-mediated IKKβ phosphorylation. DCLK1-IN-5 protects mice against inflammation-induced lung injury and sepsis[1].

Formula: C26H32ClN7O3S2

References: [1]Cai B, et al. Discovery of a doublecortin-like kinase 1 inhibitor to prevent inflammatory responses in acute lung injury. Bioorg Chem. 2024 Apr;145:107215.

CAS Number: 3028774-14-0

Molecular Weight: 590.16

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Ser/Thr Protease

• Artikelnummer: MEXHY-161471-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161471-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK