Difamilast (Standard), CAS 937782-05-3

Product Description: Difamilast (Standard) is the analytical standard of Difamilast. This product is intended for research and analytical applications. Difamilast (OPA-15406) is a topical, selective and nonsteroidal phosphodiesterase-4 (PDE4) inhibitor with particularly efficient inhibition of subtype B (IC50=11.2 nM). Difamilast can be used for the research of mild to moderate atopic dermatitis (AD)[1][2][3].

Formula: N/A

References: [1]Hanifin JM, et, al. OPA-15406, a novel, topical, nonsteroidal, selective phosphodiesterase-4 (PDE4) inhibitor, in the treatment of adult and adolescent patients with mild to moderate atopic dermatitis (AD): A phase-II randomized, double-blind, placebo-controlled study. J Am Acad Dermatol. 2016 Aug;75(2):297-305./[2]Ahluwalia J, et, al. Phosphodiesterase 4 Inhibitor Therapies for Atopic Dermatitis: Progress and Outlook. Drugs. 2017 Sep;77(13):1389-1397./[3]Soeberdt M, et, al. Small molecule drugs for the treatment of pruritus in patients with atopic dermatitis. Eur J Pharmacol. 2020 Aug 15;881:173242.

CAS Number: 937782-05-3

Molecular Weight: N/A

Research Area: Inflammation/Immunology

Target: Phosphodiesterase (PDE)

• Artikelnummer: MEXHY-109085R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-109085R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK