Diminazene, CAS 536-71-0

Product Description: Diminazene is an aromatic diamidine compound primarily utilized for the control of trypanosomiasis, a disease caused by trypanosome parasites. Diminazene primarily binds to the kinetoplast DNA (kDNA) of the trypanosomes, interfering with their replication process. Diminazene also presents avenues for novel pharmacological applications, such as acting as an activator of angiotensin-converting enzyme 2 (ACE2), and showing potential in the treatment of hypertension, rheumatoid arthritis, and as an immunomodulator[1].

Formula: C14H15N7

Citations: J Inflamm Res. 2023 Apr 17;16:1639-1652./Cell Metab. 2022 Feb 7;34(3):424-440.e7./Endocrine. 2021 Mar 30;1-9./J Inflamm Res. 2023 Apr 17;16:1639-1652./Radiat Res. 2022 Jul 29./Research Square Preprint. 2021 Mar.

References: [1]da Silva Oliveira G L, et al. Diminazene aceturate—an antiparasitic drug of antiquity: advances in pharmacology & therapeutics[J]. Pharmacological research, 2015, 102: 138-157.

CAS Number: 536-71-0

Molecular Weight: 281.32

Research Area: Infection; Inflammation/Immunology; Cardiovascular Disease

Target: Parasite

• Artikelnummer: MEXHY-W342283-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W342283-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK