Disopyramide (Standard), CAS 3737-09-5

Product Description: Disopyramide (Standard) is the analytical standard of Disopyramide. This product is intended for research and analytical applications. Disopyramide (Dicorantil) is a class IA antiarrhythmic agent with efficacy in ventricular and atrial arrhythmias. Disopyramide blocks the fast inward sodium current of cardiac muscle and prolongs the duration of cardiac action potentials. Disopyramide inhibits HERG encoded potassium channels. Disopyramide also exhibits complex protein binding, and has a potent negative inotropic action[1][2][3].

Formula: N/A

References: [1]L A Siddoway, et al. Clinical Pharmacokinetics of Disopyramide. Clin Pharmacokinet. May-Jun 1986;11(3):214-22./[2]A A Paul, et al. Inhibition of HERG Potassium Channel Current by the Class 1a Antiarrhythmic Agent Disopyramide. Biochem Biophys Res Commun. 2001 Feb 9;280(5):1243-50./[3]S V Jones, et al. Non-competitive Effects of Disopyramide at the Neuromuscular Junction: Evidence for Endplate Ion Channel Block. Br J Anaesth. 1987 Jun;59(6):776-83.

CAS Number: 3737-09-5

Molecular Weight: N/A

Research Area: Cardiovascular Disease

Target: Potassium Channel;Sodium Channel

• Artikelnummer: MEXHY-12533R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-12533R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK