Product Description: DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC) is an orally active HDAC inhibitor and metabolite of sulforaphane (HY-13755) with longer half-life and better blood-brain barrier permeability. DL-Sulforaphane N-acetyl-L-cysteine activates autophagy-mediated downregulation of α-tubulin expression through the ERK pathway and can be used in cancer research[1][2].
Applications: Cancer-programmed cell death
Formula: C11H20N2O4S3
References: [1]Liu HJ, et al. Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells. Cell Physiol Biochem. 2018;51(2):528-542./[2]Dashwood R H, et al. Dietary histone deacetylase inhibitors: from cells to mice to man[C]//Seminars in cancer biology. Academic Press, 2007, 17(5): 363-369.
CAS Number: 334829-66-2
Molecular Weight: 340.48
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Apoptosis;Drug Metabolite;HDAC