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DNMT3A-IN-3
DNMT3A-IN-3
Artikelnummer
MEXHY-158165-0
Verpackungseinheit
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Hersteller
MedChemExpress
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Product Description: DNMT3A-IN-3 is an allosteric DNA methyltransferase 3A (DNMT3A) inhibitor. DNMT3A-IN-3 binds and disrupt protein-protein interactions (PPIs) at the DNMT3A tetramer interface[1].
Formula: C30H38N6O4
References: [1]Jonathan E SandovalA, et al. First-in-Class Allosteric Inhibitors of DNMT3A Disrupt Protein-Protein Interactions and Induce Acute Myeloid Leukemia Cell Differentiation. J Med Chem. 2022 Aug 11;65(15):10554-10566. /[2]Sunzeyu Huang, et al. A novel class of selective non-nucleoside inhibitors of human DNA methyltransferase 3A. Bioorg Med Chem Lett. 2021 May 15:40:127908.
Molecular Weight: 546.66
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: DNA Methyltransferase
Formula: C30H38N6O4
References: [1]Jonathan E SandovalA, et al. First-in-Class Allosteric Inhibitors of DNMT3A Disrupt Protein-Protein Interactions and Induce Acute Myeloid Leukemia Cell Differentiation. J Med Chem. 2022 Aug 11;65(15):10554-10566. /[2]Sunzeyu Huang, et al. A novel class of selective non-nucleoside inhibitors of human DNA methyltransferase 3A. Bioorg Med Chem Lett. 2021 May 15:40:127908.
Molecular Weight: 546.66
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: DNA Methyltransferase
| Artikelnummer | MEXHY-158165-0 |
|---|---|
| Hersteller | MedChemExpress |
| Hersteller Artikelnummer | HY-158165-0 |
| Green Labware | Nein |
| Verpackungseinheit | Get quote |
| Mengeneinheit | STK |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Dr. Andreas Bergmann
