Drpitor1a, CAS 73326-98-4

Product Description: Drpitor1a is a potent Drp1 inhibitor. Drpitor1a inhibits mitochondrial ROS production, preventes mitochondrial fission, and improves right ventricular diastolic dysfunction during IR (ischemia reperfusion) injury. Drpitor1a has the potential for the research of lung cancer[1][2].

Applications: Cancer-programmed cell death

Formula: C15H8N2O2

References: [1]Wu D, et al. Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury. FASEB J. 2020 Jan;34(1):1447-1464. /[2]Wu D, et al. Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension. bioRxiv [Preprint]. 2023 Dec 23:2023.12.21.572836.

CAS Number: 73326-98-4

Molecular Weight: 248.24

Research Area: Cancer; Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Dynamin;Reactive Oxygen Species

• Artikelnummer: MEXHY-161119-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161119-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK