(E/Z)-Elafibranor, CAS 824932-88-9

Product Description: (E/Z)-Elafibranor ((E/Z)-GFT505) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively[1][2][3].

Formula: C22H24O4S

References: [1]Liu ZM, et al. Early investigational drugs targeting PPAR-α for the treatment of metabolic disease.Expert Opin Investig Drugs. 2015 May;24(5):611-21./[2]Ratziu V, et al. Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening. Gastroenterology. 2016 May;150(5):1147-1159./[3]Hanf R, et al. The dual peroxisome proliferator-activated receptor alpha/delta agonist GFT505 exerts anti-diabetic effects in db/db mice without peroxisome proliferator-activated receptor gamma-associated adverse cardiac effects.Diab Vasc Dis Res. 2014 No

CAS Number: 824932-88-9

Molecular Weight: 384.49

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: PPAR

• Artikelnummer: MEXHY-16737A-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-16737A-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK