Product Description: E3 ligase Ligand 24 (Compound 24) is a Potent Ligand for the E3 Ligase DCAF15 (IC50= 0.053 μM). Due to E3 ligase Ligand 24’s selectivity and potent binding characteristics, it is pivotal in the study of targeted protein degradation[1].
Applications: Cancer-programmed cell death
Formula: C21H26Cl2N4O5S
References: [1]Lucas SCC, et al. Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders. J Med Chem. 2024 Apr 11;67(7):5538-5566.