Elgodipine, CAS 119413-55-7

Product Description: Elgodipine (IQB-875 free base) is an orally active dihydropyridine calcium antagonist and an antianginal compound. Elgodipine inhibits both T- and L-type calcium channels (IC50: 32 and 2.3 nM). Elgodipine lowers systemic vascular resistance and improves systolic cardiac function[1][2][3].

Formula: C29H33FN2O6

References: [1]Kuhn A, et al. Hemodynamic and antiischemic effects of intravenous elgodipine, a new dihydropyridine calcium channel blocker, in patients with chronic stable angina. Cardiovasc Drugs Ther. 1995 Aug;9(4):595-600. /[2]Lepretre N, et al. Electrophysiological and radioligand binding studies of elgodipine and derivatives in portal vein myocytes. J Pharmacol Exp Ther. 1994 Dec;271(3):1209-15. /[3]Acharya DU, et al. Anti-ischaemic and haemodynamic effects of elgodipine, a potent new generation calcium antagonist, in chronic stable angina. Eur Heart J. 1994 May;15(5):665-71.

CAS Number: 119413-55-7

Molecular Weight: 524.58

Research Area: Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Calcium Channel

• Artikelnummer: MEXHY-126401-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-126401-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK