Product Description: ELOVL6-IN-4 is a potent, selective, and orally active long chain fatty acid elongase 6 (ELOVL6) inhibitor with IC50s of 79 nM and 94 nM for human and mouse ELOVL6, respectively. ELOVL6-IN-4 shows excellent selectivity over the other human ELOVL subtypes (ELOVL1, -2, -3, and -5) and mouse ELOVL3[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: C20H20F3N3O3S
References: [1]Tsuyoshi Nagase, et al. Synthesis and biological evaluation of a novel 3-sulfonyl-8-azabicyclo[3.2.1]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors. J Med Chem. 2009 Jul 23;52(14):4111-4.
CAS Number: 1170321-92-2
Molecular Weight: 439.45
Compound Purity: 98.63
Research Area: Metabolic Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: ELOVL