Product Description: Esuprone is a brain-penetrant, orally active and selective MAO A inhibitor with an IC50 of 7.3 nM. Esuprone can be used for neurological research[1][2].
Formula: C13H14O5S
References: [1]Löscher W, et al. Inhibition of monoamine oxidase type A, but not type B, is an effective means of inducing anticonvulsant activity in the kindling model of epilepsy. J Pharmacol Exp Ther. 1999 Mar;288(3):984-92./[2]Bergström M, et al. MAO-A inhibition in brain after dosing with esuprone, moclobemide and placebo in healthy volunteers: in vivo studies with positron emission tomography. Eur J Clin Pharmacol. 1997;52(2):121-8.
CAS Number: 91406-11-0
Molecular Weight: 282.31
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Monoamine Oxidase