Etoposide (Standard), CAS 33419-42-0

Product Description: Etoposide (Standard) is the analytical standard of Etoposide. This product is intended for research and analytical applications. Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy[1].

Formula: N/A

References: [1]Lee KI, et al. Etoposide induces pancreatic β-cells cytotoxicity via the JNK/ERK/GSK-3 signaling-mediated mitochondria-dependent apoptosis pathway. Toxicol In Vitro. 2016 Jul 26. pii: S0887-2333(16)30147-3./[2]Calvani M, det al. Etoposide-Anti-Human VEGF a new strategy against human melanoma cells expressing stem-like traits. Oncotarget. 2016 Jun 9. doi: 10.18632/oncotarget.9939./[3]Fuchs, J., et al. Comparative activity of NSC 119875, NSC 109724, NSC 123127, NSC 241240, and etoposide in heterotransplanted hepatoblastoma. Cancer, 1998. 83(11): p. 2400-7./[4]Hande KR, et al. The Importance of Drug Scheduling in Cancer Chemotherapy: Etoposide as an Example. Oncologist. 1996;1(4):234-239./[5]Cui D, et al. FBXW7 Confers Radiation Survival by Targeting p53 for Degradation.Cell Rep. 2020 Jan 14;30(2):497-509.e4.

CAS Number: 33419-42-0

Molecular Weight: N/A

Research Area: Cancer; Infection

Target: Antibiotic;Apoptosis;Autophagy;Bacterial;Mitophagy;Topoisomerase

• Artikelnummer: MEXHY-13629R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-13629R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK