Finerenone (Standard), CAS 1050477-31-0

Product Description: Finerenone (Standard) is the analytical standard of Finerenone. This product is intended for research and analytical applications. Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease[1][2].

Formula: N/A

References: [1]Bärfacker L, et al. Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseases. ChemMedChem. 2012;7(8):1385-1403./[2]González-Blázquez R, et al. Finerenone Attenuates Endothelial Dysfunction and Albuminuria in a Chronic Kidney Disease Model by a Reduction in Oxidative Stress. Front Pharmacol. 2018;9:1131. Published 2018 Oct 9.

CAS Number: 1050477-31-0

Molecular Weight: N/A

Research Area: Cardiovascular Disease

Target: Mineralocorticoid Receptor

• Artikelnummer: MEXHY-111372R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-111372R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK