Flubendazole (Standard), CAS 31430-15-6

Product Description: Flubendazole (Standard) is the analytical standard of Flubendazole. This product is intended for research and analytical applications. Flubendazole is an anthelmintic drug based on altering microtubule structure, inhibition of tubulin polymerization and disruption of microtubule function. Flubendazole induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy. Flubendazole induces P53 expression and reduced Cyclin B1 and p-cdc2 expression. Flubendazole is an antitumor agent. Flubendazole can be used for worm and intestinal parasites[1][2].

Formula: N/A

References: [1]Zhou X, et al. Flubendazole inhibits glioma proliferation by G2/M cell cycle arrest and pro-apoptosis. Cell Death Discov. 2018 Feb 14;4:18./[2]Shichong Lin, et al. Flubendazole demonstrates valid antitumor effects by inhibiting STAT3 and activating autophagy. J Exp Clin Cancer Res. 2019 Jul 8;38(1):293.

CAS Number: 31430-15-6

Molecular Weight: N/A

Research Area: Cancer; Infection

Target: Apoptosis;Autophagy;MDM-2/p53;Microtubule/Tubulin;Parasite;STAT

• Artikelnummer: MEXHY-B0294R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0294R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK