Gefitinib, CAS 184475-35-2

Description: Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell lung cancers. Gefitinib administration RESULTS in the development of the EGFR C797S resistance mutation.

CAS Number: 184475-35-2

Formula: C22H24ClFN4O3

Molecular Weight: 446,9

References: Noro R, et al. Gefitinib (IRESSA) sensitive lung cancer cell lines show phosphorylation of Akt without ligand stimulation. BMC Cancer. 2006 Dec 6;6:277.

• Artikelnummer: TGMT1181-500mg
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: T1181-500mg
• Verpackungseinheit: 500 mg
• Mengeneinheit: STK