GNF-PF-3777, CAS 77603-42-0

Product Description: GNF-PF-3777 (8-Nitrotryptanthrin) is a potent human indoleamine 2,3-dioxygenase 2 (hIDO2) inhibitor which significantly reduces IDO2 activity with Ki of 0.97 μM.

Applications: Neuroscience-Neuromodulation

Formula: C15H7N3O4

References: [1]Li J, et al. Establishment of a human indoleamine 2, 3-dioxygenase 2 (hIDO2) bioassay system and discovery of tryptanthrin derivatives as potent hIDO2 inhibitors. Eur J Med Chem. 2016 Nov 10;123:171-9./[2]Hwang JM, et al. Design, synthesis, and structure-activity relationship studies of tryptanthrins as antitubercular agents. J Nat Prod. 2013 Mar 22;76(3):354-67./[3]Scovill J, et al. Antitrypanosomal activities of tryptanthrins. Antimicrob Agents Chemother. 2002 Mar;46(3):882-3.

CAS Number: 77603-42-0

Molecular Weight: 293.23

Compound Purity: 98.56

Research Area: Neurological Disease

Solubility: DMSO : 6.4 mg/mL (warming)

Target: Indoleamine 2,3-Dioxygenase (IDO)

• Artikelnummer: MEXHY-100687-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-100687-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK