Product Description: GSK2292767 is a potent and selective inhibitor of PI3Kδ, with a pIC50 of 10.1. GSK2292767 showing greater than 500-fold selective over the other PI3K isoforms. GSK2292767 can be used for the research of respiratory disease[1].
Applications: COVID-19-immunoregulation
Formula: C24H28N6O5S
References: [1]Down K, et, al. Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease. J Med Chem. 2015 Sep 24; 58(18): 7381-99.
CAS Number: 1254036-66-2
Molecular Weight: 512.58
Compound Purity: 98.89
Research Area: Inflammation/Immunology
Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)