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HC-067047 (hydrochloride), CAS 1481646-76-7
HC-067047 (hydrochloride), CAS 1481646-76-7
Artikelnummer
MEXHY-W721480-0
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MedChemExpress
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Product Description: HC-067047 hydrochloride is a potent and selective TRPV4 antagonist and reversibly inhibits currents through the human, rat, and mouse TRPV4 orthologs with IC50 values of 48 nM, 133 nM, and 17 nM, respectively[1].
Formula: C26H29ClF3N3O2
References: [1]Everaerts W et al. Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19084-9./[2]Xing Y, et al. Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment. Yonsei Med J. 2018 Nov;59(9):1131-1137.
CAS Number: 1481646-76-7
Molecular Weight: 507.98
Target: TRP Channel
Formula: C26H29ClF3N3O2
References: [1]Everaerts W et al. Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19084-9./[2]Xing Y, et al. Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment. Yonsei Med J. 2018 Nov;59(9):1131-1137.
CAS Number: 1481646-76-7
Molecular Weight: 507.98
Target: TRP Channel
| Artikelnummer | MEXHY-W721480-0 |
|---|---|
| Hersteller | MedChemExpress |
| Hersteller Artikelnummer | HY-W721480-0 |
| Green Labware | Nein |
| Verpackungseinheit | Get quote |
| Mengeneinheit | STK |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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