hCAI/II-IN-8

Product Description: hCAI/II-IN-8 (Compound 8) is a hydrazide derivative based on 4-hydroxybenzaldehyde. hCAI/II-IN-8 primarily targets human carbonic anhydrase isomerase I (hCA I) and II (hCA II) for inhibition (IC50 = 21.35 ± 0.39 nM (hCA I); 7.12 ± 0.12 nM (hCA II)). hCAI/II-IN-8 inhibits AChE and BChE as well(IC50 = 46.27 ±0.75 nM (AChE); 43.38 ± 0.83 nM (BChE)). [1].[1].

Formula: C22H20N4O3

References: [1]Çakmak, R.et al. Synthesis of Novel Hydrazide–Hydrazone Compounds and In Vitro and In Silico Investigation of Their Biological Activities against AChE, BChE, and hCA I and II. ACS Omega, 9(18), 20030–20041.

Molecular Weight: 388.42

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Carbonic Anhydrase;Cholinesterase (ChE)

• Artikelnummer: MEXHY-161507-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161507-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK