Product Description: HCTZ-CH2-HCTZ is an isomer of HCTZ (HY-B0252). Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway[1][2].
Formula: C15H16Cl2N6O8S4
References: [1]Duarte, J.D. and R.M. Cooper-DeHoff, Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics. Expert Rev Cardiovasc Ther, 2010. 8(6): p. 793-802./[2]X Fang, et al. Purification and identification of an impurity in bulk hydrochlorothiazide. J Pharm Sci. 2001 Nov;90(11):1800-9.
CAS Number: 402824-96-8
Molecular Weight: 607.49
Research Area: Others
Target: Drug Intermediate;TGF-β Receptor