HDAC6-IN-3, CAS 3023019-99-7

Product Description: HDAC6-IN-3 (Compound 14), an antiprostate cancer agent, is a potent, orally active HDAC6 inhibitor with IC50s ranging from 0.02-1.54 μM for HDAC1/2/3/6/8/10. HDAC6-IN-3 is also an effective MAO-A (IC50=0.79 μM) and LSD1 inhibitor[1]. HDAC6-IN-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C19H27N3O3

References: [1]Ojha R, et al. Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent. J Med Chem. 2021;64(24):17824-17845.

CAS Number: 3023019-99-7

Molecular Weight: 345.44

Compound Purity: 98.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: HDAC;Histone Demethylase

• Artikelnummer: MEXHY-145259-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-145259-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK